Endocrine Abstracts

Background: Patients with type 2 diabetes mellitus (T2DM) have elevated risk of coronary artery disease (CAD) development. In this population CAD often proceedsasymptomatically, especially if cardiac autonomic neuropathy (CAN) is present. Our aim was to assess relation between glycemia control and asymptomatic CAD inT2DM pts. Materials and methods: Participants were 160 T2DM patients without documented CAD divided into four groups (Gr.) according to HbA1c levels: Gr. 1 -HbA1c6...

Background and aims: Mortality rate from cardiovascular disease (CV) including sudden death (SD) is pronounced in type 2 diabetic (T2DM) patients with cardiac autonomic neuropathy (CAN) and/or complex ventricular arrhythmias (CVA). Early repolarization (ER) is also considered to be a significant risk factor for SD. The aim of the study was to evaluation the relation between CAN, CVA and ER in T2DM patients.Materials and methods: Participants were 44 T2DM...

The aim: To reveal relation between altered left ventricular (LV) geometry (G) and contractile ability (CA) in nonbese type 2 diabetic (DM2) patients with mild hypertension (MH).Materials and methods: BP at rest, 24-h ambulatory BP monitoring and echocardiography were investigated in 70 non-obese males, aged 25–50 yrs. They were divided into the following groups: Gr.1, n=15 – DM2 and normal BP, fasting C-peptide (C-p, ng/ml) 4.3±0.9...

Our aim was to evaluate the efficacy of a structured outpatient education and treatment program (SOETP) in type 1 diabetes patients (T1DM) patients during preconception care (PC) and pregnancy, and its effect on pregnancy outcomes. Study Methods: In total 173 women with T1DM were supervised. Maternal age was 28±8 yrs and diabetes duration - 12±7yrs. SOETP combined group and individual training. Stage 1 - preconception care (group and individual training). Stage 2 - i...

It is clear that effective control of blood glucose, hypertension and dyslipidemia, may prevent development of vascular complications in type 2 diabetes (T2DM).The aim of the present work was to reveal correlation between glycemia levels and mortality rate in T2DM patients (pts) with prior myocardial infarction (PMI).Materials: Totally, 131 T2DM pts with PMI were studied (mean age – 57.2±3.1 yrs; diabetes duration – ...

Background: It is generally believed that glycemic targets in diabetic pregnancies should mimic those found in normal pregnancies.Aim: The aim of the present work was to reveal how glycemia indices in pregnant patients with type 1 diabetes mellitus (T1DM), their infants’ birth weight (IBW).Methods: Totally, 128 pregnant women with T1DM were enrolled in the study (mean age – 26±7 yrs; diabetes duration – 10.2&#17...

Background: Impaired circadian blood pressure (BP) variation is a frequent phenomenon in hypertensive type 2 diabetic (T2DM) patients (pts), and is considered a risk factor for development of cardiovascular complication. The aim - to assess the effect of Lacidipine on left ventricular mass (LVM) and BP in hypertensive T2DM pts.Materials and methods: Totally 32 T2DM pts with mild-to-moderate hypertension (20 m/12 f, mean age 57±9.6 yrs) were allocate...